- PERIPHEBA is a complementary formula designed to support both the symptoms and causes of peripheral neuropathy. PERIPHEBA contains methylcobalamin 500 micrograms which is the active form of vitamin B12 to be easily absorbed than cyanocobalamine. PERIPHEBA also contains vitamin B1 as benfotiamine 150 mg which is absorbed 3.6 times more than the standard form of thiamine plus Vitamin B6, Folic acid, B2, and B5 to support Poly Neuropathy, Vision, Energy, brain, and heart, in a once-a-day capsule.
- PERIPHEBA will change the course of neuropathy care.
Ingredients
- Ingredients Amount per serving
- Benfotiamine 150 mg
- Vitamin B2 (as Riboflavin) 10 mg
- Vitamin B6 (as Pyridoxine hydrochloride) 10 mg
- Folate (folic acid,Vitamin B9) 170 mcg
- Vitamin B12 (as Methyl cobalamin) 500 mcg
- Vitamin B5 (as Calcium D-Pantothenate) 50 mg
Vitamin B1 -Benfotiamine
Benfotiamine is a fat-soluble version of vitamin B1 and is thus much more bioavailable and absorbed 3.6 times more than the standard form of thiamine (1&4)
1- Benfotiamine Protects Nerve Cells from Inflammation (2)
2-Benfotiamine Protects Our Blood Vessels from Damage (3)
3- Benfotiamine Reduces Neuropathic Pain, and improves sensation (3)
Vitamin B12-Methylcobalamin
Methylcobalamin in PERIPHEBA IS the activated form of vitamin B12 unlike Cyanocobalamine which is an inactive form and needs a long time to be converted to methylcobalamin,which is effective in peripheral neuropathies (5)
1-Methylcobalamine alleviated pain behaviors in diabetic polyneuropathy, low back pain, sciatica, and neuralgia. (6)
2-The efficacy of oral vitamin B-12 supplementation was similar to that of hydroxocobalamin injections and can be used as an alternative to hydroxocobalamin injections to treat patients with low values of serum vitamin B-12 (7)
1- int J Clin Pharmacology Ther. 1996 Feb;34(2):47-50,
2- Shoeb, M., & Ramana, K. (2012, January 1). The anti-inflammatory effects of Benfotiamine are mediated through the regulation of the arachidonic acid pathway in macrophages. Retrieved May 22, 2020, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249497/.
3-Stracke, H., Lindemann, A., & Federlin, K. (1996). A benfotiamine-vitamin B combination in the treatment of diabetic polyneuropathy. Retrieved May 22, 2020, from https://www.ncbi.nlm.nih.gov/pubmed/8886748.
4- 1.Haupt, E., Ledermann, H., & Köpcke, W. (2005, February). Benfotiamine in treating diabetic polyneuropathy--a three-week randomized, controlled pilot study (BEDIP study). Retrieved May 22, 2020, from https://www.ncbi.nlm.nih.gov/pubmed/15726875
5-European Journal of Clinical Nutrition (2015) 69, 530© 2015
6- Methylcobalamin: A Potential Vitamin of Pain Killer - PMC (nih.gov)
7-The American Journal of Clinical Nutrition Volume 108, Issue 1,